How does DNA affect your medication?
No two people will respond to a medication in the exact same way. Here our some of the major factors your genetic makeup determines.
- Drug Absorption – DNA can affect how medication moves through your body, and how quickly a drug will enter into and move throughout your bloodstream.
- Drug Metabolism – Once you’ve absorbed a medication, your DNA determines how fast your body uses the medicine, which health professionals call the “metabolization rate.” If your body metabolizes medication very quickly, your doctor may want to increase dosage. On the other hand, slower metabolization puts patients at risk of negative side effects; smaller doses are often helpful in these cases.
- Drug Activity – What works for certain people may not work for others. A body’s response to a medication can vary greatly from person to person because of genetic composition. Understanding how an individual will respond to a certain drug can help avoid unpleasant side-effects and limit the number of medications a patient needs to take.
With pharmacogenomic testing, you and your doctor can determine what medications and dosages will work best for your unique genetic profile.